| Date | Issuer | Insider | Transaction | Amount | New Balance ⓘ 
                                    The balance of securities held by registered holder at the time of the transaction. Insiders may direct multiple registered holders and hold multiple security types.
                                 | |
|---|---|---|---|---|---|---|
| Filed 2025-03-27 14:01 Tx date 2025-03-25 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $308,400 +60,000 vol $5.14 each | 310,000 | |
| Filed 2024-05-22 23:23 Tx date 2024-05-13 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $277,200 +70,000 vol $3.96 each | 250,000 | |
| Filed 2024-04-01 08:55 Tx date 2024-02-27 | $CCCP. Coco Pool Corp. | Kowalski, Mark 
                                4 - Director of Issuer, 5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options52 - Expiration of options | -20,000 vol | 88,709 | |
| Filed 2023-08-20 01:08 Tx date 2023-08-18 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares11 - Acquisition or disposition carried out privately | $56,000 +8,000 vol $7.00 each | 8,000 | |
| Filed 2023-08-20 01:07 Tx date 2023-05-18 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares00 - Opening Balance-Initial SEDI Report | |||
| Filed 2023-05-19 19:30 Tx date 2023-05-18 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $1,231,200 +180,000 vol $6.84 each | 180,000 | |
| Filed 2023-05-19 19:28 Tx date 2023-05-18 | $EPRX Eupraxia Pharmaceuticals Inc. | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options00 - Opening Balance-Initial SEDI Report | |||
| Filed 2016-03-29 Tx date 2016-03-15 | $ABUS Arbutus Biopharma Corporation | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $334,900 +85,000 vol $3.94 each | 260,000 | |
| Filed 2015-12-23 Tx date 2015-12-03 | $TKMR Arbutus Biopharma Corporation | Kowalski, Mark Marion 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options00 - Opening Balance-Initial SEDI Report | 175,000 |