| Date | Issuer | Insider | Transaction | Amount | New Balance ⓘ 
                                    The balance of securities held by registered holder at the time of the transaction. Insiders may direct multiple registered holders and hold multiple security types.
                                 | |
|---|---|---|---|---|---|---|
| Filed 2018-12-07 Tx date 2018-12-04 | $PLI Prometic Life Sciences Inc. | Kenworthy, Charles 
                                4 - Director of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $139,999 +181,818 vol $0.77 each | 389,724 | |
| Filed 2017-05-23 Tx date 2017-05-18 | $PLI ProMetic Life Sciences Inc. | Kenworthy, Charles 
                                4 - Director of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $143,579 +69,362 vol $2.07 each | 207,906 | |
| Filed 2016-05-30 Tx date 2016-05-25 | $PLI ProMetic Life Sciences Inc. | Kenworthy, Charles 
                                4 - Director of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | $118,686 +39,562 vol $3.00 each | 138,544 | |
| Filed 2015-06-12 Tx date 2015-06-08 | $PLI ProMetic Life Sciences Inc. | Kenworthy, Charles 
                                4 - Director of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | +48,426 vol | 98,982 |