| Date | Issuer | Insider | Transaction | Amount | New Balance ⓘ 
                                    The balance of securities held by registered holder at the time of the transaction. Insiders may direct multiple registered holders and hold multiple security types.
                                 | |
|---|---|---|---|---|---|---|
| Filed 2025-05-21 18:52 Tx date 2025-03-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Warrants55 - Expiration of warrants | $-156,250 -1,562,500 vol $0.10 each | 0 | |
| Filed 2024-09-12 09:22 Tx date 2024-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares11 - Acquisition or disposition carried out privately | $250,000 +2,500,000 vol $0.10 each | 17,130,333 | |
| Filed 2024-09-12 09:08 Tx date 2024-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Warrants54 - Exercise of warrants | $-250,000 -2,500,000 vol $0.10 each | 1,562,500 | |
| Filed 2023-09-18 09:21 Tx date 2023-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Warrants53 - Grant of warrants | $250,000 +2,500,000 vol $0.10 each | 4,062,500 | |
| Filed 2023-09-18 09:19 Tx date 2023-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Warrants53 - Grant of warrants | $156,250 +1,562,500 vol $0.10 each | 1,562,500 | |
| Filed 2023-09-18 09:16 Tx date 2023-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Warrants00 - Opening Balance-Initial SEDI Report | |||
| Filed 2023-09-18 09:13 Tx date 2023-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares10 - Acquisition or disposition in the public market | $250,000 +3,125,000 vol $0.08 each | 14,630,333 | |
| Filed 2023-09-18 08:56 Tx date 2023-09-11 | $KNE Kane Biotech Inc. | Renaud, Richard J. 
                                3 - 10% Security Holder of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares00 - Opening Balance-Initial SEDI Report | 11,505,333 |