| Date | Issuer | Insider | Transaction | Amount | New Balance ⓘ 
                                    The balance of securities held by registered holder at the time of the transaction. Insiders may direct multiple registered holders and hold multiple security types.
                                 | |
|---|---|---|---|---|---|---|
| Filed 2019-05-08 20:15 Tx date 2019-05-06 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | +10,000 vol | 82,503 | |
| Filed 2018-06-14 Tx date 2018-06-12 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | +6,285 vol | 72,503 | |
| Filed 2017-12-20 Tx date 2017-12-19 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options51 - Exercise of options | -13,774 vol | 66,218 | |
| Filed 2017-12-20 Tx date 2017-12-19 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares51 - Exercise of options | $65,426 +13,774 vol $4.75 each | 137,223 | |
| Filed 2017-06-15 Tx date 2017-06-12 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options50 - Grant of options | +6,285 vol | 79,992 | |
| Filed 2017-05-05 Tx date 2017-04-27 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Options00 - Opening Balance-Initial SEDI Report | 73,707 | ||
| Filed 2017-05-05 Tx date 2017-04-27 | $ZYME Zymeworks Inc. | Bedford, Nick 
                                5 - Senior Officer of Issuer
                             
                                
                                
                                
                                    Direct Ownership
                                
                             | Common Shares00 - Opening Balance-Initial SEDI Report | 123,449 |